Panorama vs Harmony - Side-by-Side Comparison
| Feature | Panorama | Harmony |
|---|---|---|
| Technology | SNP-based technology that separates fetal & maternal DNA more precisely | DANSR targeted sequencing + FORTE algorithm |
| What It Screens For | Broad panel: trisomies, triploidy, sex chromosome conditions, microdeletions incl. 22q11.2 | Focused panel: trisomies 21, 18, 13; optional sex chromosomes & microdeletions |
| Accuracy | >99% sensitivity for trisomy 21, 13, triploidy; strong performance with low fetal fraction | >99% detection for trisomy 21; very low false-positive rate (<0.1%) |
| Best Performance In | Low fetal fraction pregnancies; early testing; broader condition detection | Singleton, twin, and donor-egg pregnancies |
| Earliest Testing Week | From 9 weeks | From 10 weeks |
| Turnaround Time | 7–10 days (may vary) | 7–10 days (may vary) |
| Cost | €550 | €500 |
| Best For | Parents wanting more comprehensive screening, including microdeletions and early testing | Parents wanting focused, reliable screening for the most common conditions |
Summary
Choosing a prenatal screening test can feel overwhelming, especially when you're trying to do what's best for your baby. Panorama and Harmony are two of the most trusted non-invasive prenatal tests (NIPTs). Both check your baby's DNA through a simple blood test, but they offer slightly different benefits.
Panorama
Panorama looks at a wider range of conditions. It uses advanced technology that can separate your baby's DNA from yours more clearly, which helps give accurate results even very early in pregnancy or when the fetal DNA level is low. It can be done from 9 weeks and screens for common chromosomal conditions, sex chromosome differences, and certain microdeletions.
Harmony
Harmony focuses on the most common chromosomal conditions, like Down syndrome. It's a reliable option for many pregnancies, including twins and donor-egg pregnancies. Harmony can be done from 10 weeks and has a very low false-positive rate.
Which Test Is Right for You?
- If you want the broadest information early in pregnancy, Panorama may be the better fit.
- If you prefer a focused test for the most common conditions, Harmony is a strong, trusted option.
Both tests are safe, non-invasive, and help you plan confidently for your pregnancy.